Talk:Glutamine
From Academic Kids
I've modified this:
In people living with diseases that put long term strain on the immune system (like HIV), glutamine is burned at a higher rate. Glutamine is also used in the digestive process and -- if not supplemented -- can lead to wasting.
Glutamine may have something to do with cachexia, but the relationship between the two things is certainly not as simple as this implies. It would be nice to be able to quote a reference here. -- Someone else 02:52 Apr 12, 2003 (UTC)
theraputic uses of glutamine
My wife, who has undergone radiation treatment to her abdominal area and is now suffering from radiation enteritis, was told by her physician that glutamine supplementation has been shown to help heal the villi lining the bowel. My subsequent reading on the web has indicated this to be a commonly accepted treatment regimen for people with radiation enteritis, irritable bowel disease, or other similar problems. Glutamine also is prescribed to HIV patients, and to patients receiving radiation and chemotherapy.
Adverse effects
This article concentrates on adverse effects of glutamine consumption. However, it gives zero references. This article desperately needs some work in this area. In particular, someone who knows this stuff needs to firm up the documentation. I'm not a biochemist, so I don't know how much of this information is well-supported and how much is hearsay. Gwimpey 05:59, Apr 14, 2005 (UTC)
- OK, most of this page was a copyvio. I removed the offending material and put a link to the source Gwimpey 06:18, Apr 14, 2005 (UTC)
rewrite
Since very little of relevance was left, I went ahead and rewrote the article. It could still use more help (as could a lot of the other amino acid articles-- I may get around to this). In particular, I removed this:
It is converted into the excitotoxin glutamate within neurons. Glutamine is then transported to the neuron and by the enzyme glutaminase, it is converted to glutamate--the potential excitotoxin. Unless it accumulates outside the brain cell it is harmless.
While arguably true, this tends to create the impression that glutamine is notable as a neurotoxin, which is false. Molybdenumblue 23:52, 16 Apr 2005 (UTC)
