GC
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GC may stand for:
- Gabriel Centaurio
- GameCube
- Games Convention
- Garbage collection
- Gas chromatography
- General contractor
- General Catalogue (astronomy)
- Guanine-Cytosine (genetics)
- General counsel
- Goose Creek (South Carolina)
- Guidance counselor
- George Cross
- Gigacoulomb (GC), an SI unit for electric charge equal to 109</sub> coulomb
- Gliomatosis cerebri
- Glivenko-Cantelli
- Global citizenship
- Global Crossing
- Goldbach's conjecture
- Gold Coins
- Goshen College
- Grand champion
- Graphics calculator
- Graphics context (X11)
- Grasshopper-Club, a football club from Zürich
- Great circle (navigation)
- Greensboro College
- Greenville College
- Grilled Cheese
- Ground control
- Group Captain (RAF)
- Guardia Civil (Spain)