Inhibitor

An inhibitor is a type of effector (biology) that decreases or prevents a chemical reaction. They are often called negative catalysts. Inhibitors are often used as medicines to decrease the rate of enzyme mediated reactions, but they can also act as poisons. Other examples include antioxidants and antipolymerization agents. A corrosion inhibitor is added to antifreeze (coolant) used in engines.

Inhibitors and Enzymes

Inhibitors also affect enzymes, they are divided into three kinds:

Irreversible inhibitors which often react covalently with the enzyme molecule they permentantly stop the enzyme working.

Competitive inhibitors compete with the substrate for the active site but do not react in it and stop it being used, a high concentration of substate stops this happening.

You can also get Allosteric Inhibitors which bind to another part of the enzyme and stop it working, this isn't permenant. The body often uses this with the product being the allosteric inhibitor which stops the substance being produced.

Inhibitions in Behaviour

Inhibitions in behavior may have a positive connotation (behaving properly, responsibly) or a negative one (being shy, boring, not brave). They are reduced by common forms of intoxication like alcohol.

See also:

receptor antagonistTemplate:Chem-stub

de:Inhibitor fr:Inhibiteur pl:Inhibitor

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